Maybe I'm reaching, but I'm starting to feel a sort of full-circle or slow role-reversal thing going on? Eve's in a spot that's thematically kinda like Hannah was at the start of the comic, and vice versa.

At the start, Hannah was a generally contented, lively, impulsive, well-connected person, who was in a committed relationship, and seemed to have all the answers. Eve was a disatisfied, listless loner, recently became single, felt uncertain about her future or what was right, and had grown distant from most of her former relationships. If you flip Hannah and Eve now, as we get down to the end... it's not a perfect fit, but it's weird how they sorta fit into each other's shoes, circa the start of things.

Plenty has changed for both of them, but it seems like there might be something here?
Maybe it's Eve's turn to be Hannah's supportive foil and quasi Life Coach, as she figures out her own future? *shrug*